Quick Answer NMN + TMG 1500mg delivers 750mg of Nicotinamide Mononucleotide and 750mg of Trimethylglycine per serving in a balanced 1:1 ratio. NMN is a direct NAD+ precursor; TMG replenishes the methyl groups consumed during NAD+ synthesis. 60 vegan capsules · 30 servings · third-party tested every batch · UK manufactured · from £27.99.
Longevity Series 1500mg · 1:1 Ratio Subscribe · save 10%

NMN + TMG

Next-Gen NAD+ Complex · 60 Capsules · 30 Servings · Balanced 1:1 Ratio

★★★★★ 4.8 / 287 reviews · Read reviews Verified ✓
NAD+ Precursor
750mg
Pure NMN
Nicotinamide Mononucleotide · Direct NAD+ precursor
Methylation
750mg
Pure TMG
Trimethylglycine · Replenishes methyl groups used by NMN
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Lab VerifiedCoA on request
Third-party tested — every batch
Certificate of Analysis available on request — email with your batch number
750mg
NMN · per serving
750mg Pure NMN per serving — high-strength dual-ingredient format.
1:1
Balanced ratio
Equal NMN + TMG. Balanced to support methylation efficiency.
100%
Batches tested
Third-party verified. Every batch, ISO/IEC 17025-accredited lab.
🇬🇧
UK Made
UK manufactured. Manufactured and quality-checked in the United Kingdom.
What to expect

A realistic timeline for
what you'll notice.

NMN works upstream in your cellular energy pathway — not as a stimulant. Here is what customers report and when. Individual results vary and depend on baseline NAD+ levels, age, diet, and consistency of daily use.

Days
1–7
Nothing dramatic — that's expected
NMN acts at a cellular level, raising NAD+ over time rather than producing an immediate effect. Most customers report no dramatic change in the first week. This is normal — cellular NAD+ levels rise gradually with consistent daily dosing.
Weeks
2–4
Improved energy consistency and clarity
The most commonly reported early changes are more consistent energy across the day and improved mental clarity, particularly in the afternoon. Customers who start at a lower NAD+ baseline often report this phase earlier. Individual results vary.
Weeks
5–10
Sustained energy, sleep quality, and recovery
By weeks 5–8, customers commonly report improved sleep quality, faster morning recovery, and more sustained physical energy. Some report improved mood stability and reduced brain fog — consistent with TMG's methylation support role.
Month
3+
The clearest signal: stopping
Customers who pause after 90+ days of consistent use commonly report a gradual return toward their prior energy baseline over 2–3 weeks. This is the most reliable signal that the protocol is working. Daily consistent use is recommended for continued support.
★★★★★
"Three months in. My afternoon energy is genuinely different — more consistent, less reliant on coffee. The TMG pairing made sense to me scientifically and I'm glad I went for it over plain NMN."
— James T. · Verified buyer · 3 months subscription Verified ✓
The Formula

Built on published research

Two molecules, one protocol. Full-dose transparency. No proprietary blends. No fillers in the active formula.

750
mg NMN per serving
Direct NAD+ precursor
Nicotinamide Mononucleotide (NMN) is one biochemical step from NAD+. NAD+ is involved in hundreds of metabolic processes and declines significantly with age. NMN supplementation is one of the most studied approaches to supporting NAD+ levels in humans.
750
mg TMG per serving
Methylation balance partner
Trimethylglycine (betaine) is a methyl donor. NMN metabolism consumes methyl groups — over time this can deplete available methylation capacity. TMG replenishes these groups. Our 1:1 ratio supports the full NMN pathway, not just NAD+ synthesis.
1:1
Ratio
Why it matters
The complete stack
Many NMN products contain NMN alone. The methylation cost of NAD+ synthesis is well-documented in the research literature. We formulate NMN and TMG at equal 750mg doses — a complete stack in one product rather than requiring customers to source two supplements separately.
Ingredient Profile

What's inside — and why.

Full-dose transparency. No proprietary blends. You know exactly what you're taking and at what dose.

750mg
NMN
Nicotinamide Mononucleotide · CAS 1094-61-7

NMN — a direct NAD+ precursor for cellular energy support

Nicotinamide Mononucleotide (NMN) is a naturally occurring molecule found in trace amounts in certain foods. As a direct precursor to NAD+, it enters the NAD+ biosynthesis pathway efficiently. NAD+ is a coenzyme central to mitochondrial energy production and many other cellular functions.

NAD+ levels decline with age. NMN supplementation is one of the most researched approaches in the longevity science field. Our formulation delivers a high, research-aligned dose in a single daily serving.

  • 750mg per serving — high-strength, single-dose format
  • Direct NAD+ precursor — one biochemical step from NAD+
  • Third-party tested, third-party identity and purity verified
  • No proprietary blend — full dose on label
  • Gluten-free · dairy-free · non-GMO · 100% vegan
750mg
TMG
Trimethylglycine (Betaine) · CAS 107-43-7

TMG — the methylation partner that completes the stack

Trimethylglycine (betaine) is a naturally occurring compound found in foods such as beetroot, spinach, and wholegrains. It is one of the body's primary methyl donors, contributing to homocysteine metabolism and the maintenance of normal methylation capacity.

NMN metabolism utilises methyl groups. Including TMG at a matched dose is designed to replenish this demand — making NMN + TMG a more complete formula than NMN alone. We formulate at a balanced 1:1 ratio rather than a token TMG inclusion.

  • 750mg per serving — matched 1:1 with NMN dose
  • Supports normal methylation capacity
  • Contributes to normal homocysteine metabolism
  • Naturally derived from plant sources
  • No separate supplement required — built into the formula
Supplement Facts
Serving Size: 2 Capsules  |  Servings Per Container: 30
IngredientAmount Per Serving% DV
NMN (Nicotinamide Mononucleotide)750 mg
TMG (Trimethylglycine)750 mg
Cellulose (Vegetable Capsule)
Magnesium Stearate (vegetable source)
Silicon Dioxide
† Daily Value not established.
Free from: Gluten, Dairy, Soy, Nuts, GMOs. 100% Vegan. Non-GMO verified.
How we compare

Vitality vs the alternatives

What mattersVitality NMN + TMGTypical NMN brand
NMN dose per serving 750mg Pure NMN125–500mg typical
TMG included 750mg — matched 1:1Often absent or token dose
Dose ratio transparency Fully labelled — no blendsOften proprietary blend
Third-party testing Every batch, ISO-accreditedRarely disclosed
CoA available On request, same dayUsually unavailable
UK manufactured UK-based facilityOften overseas, unverified
Quality assurance

Third-party tested.
Every batch.

We test every batch at an ISO/IEC 17025-accredited independent laboratory before release. The CoA confirms identity and purity of both NMN and TMG, and the absence of heavy metals, pesticides, and microbiological contaminants.

  • ISO/IEC 17025 accredited laboratory
  • NMN and TMG identity confirmed by HPLC
  • Heavy metals panel — every batch
  • Microbiological testing — every batch
  • CoA available on request — email with batch number

Certificate of Analysis

Available for every production batch. Email us your batch number and we'll send it the same day.

Tests performed — every batch
NMN Identity (HPLC)
TMG Identity (HPLC)
Purity
Heavy metals
Microbiology
Pesticide residues
Customer reviews

What customers say

4.8
★★★★★
287 verified reviews
5★
230
4★
40
3★
11
2★
4
1★
2
★★★★★
Excellent
★★★★★3 weeks ago

The combination makes sense

Was taking NMN alone before. Switched to this when I read about the methylation issue. Six weeks in — the difference in how I feel by mid-afternoon is real. More consistent, less reliance on my third coffee. Proper dose on the label.
— Michael S. · 2 monthsVerified ✓
★★★★★5 weeks ago

Sleep is noticeably better

Started as part of a longevity stack. The sleep improvement was unexpected — by week 4 I was waking up noticeably more refreshed. Hard to attribute everything to NMN but the only variable I changed was starting this.
— Claire W. · Subscribed 2 monthsVerified ✓
★★★★☆1 month ago

Good product — takes patience

On my second pouch. First month I didn't notice much. Now definitely feeling more energy stability. CoA came through same day I asked for it — that transparency matters to me. 4 stars because of slow onset, but that's probably how it works.
— Richard B. · Subscribed 2 monthsVerified ✓
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Common questions

Frequently asked

NMN + TMG 1500mg delivers 750mg of Nicotinamide Mononucleotide (NMN) and 750mg of Trimethylglycine (TMG) per serving in a balanced 1:1 ratio. NMN is a direct precursor to NAD+, a coenzyme involved in cellular energy metabolism that declines with age. TMG is a methyl donor that replenishes the methyl groups consumed when NMN is converted to NAD+. Together they support NAD+ levels and methylation balance as a food supplement.
When NMN is converted to NAD+, the process consumes methyl groups from the body's methylation pool. Over time, sustained NMN supplementation without replenishment can deplete available methylation capacity — which plays a role in homocysteine metabolism and other cellular processes. TMG (Trimethylglycine) is one of the body's primary methyl donors and directly replenishes what NMN metabolism uses. We include 750mg TMG matched equally to 750mg NMN — not a token dose.
Take 2 capsules daily with water, preferably in the morning. NAD+ is involved in energy metabolism and most customers find morning dosing works best — some report that taking NMN later in the day affects sleep onset, though individual responses vary. Take consistently every day for best results. Do not exceed the recommended daily dose.
NMN acts at a cellular level rather than producing an immediate stimulant effect. Most customers report no dramatic change in the first week — this is expected. The most commonly reported early changes (weeks 2–4) are improved energy consistency and afternoon clarity. By weeks 5–10, customers report more sustained energy, improved sleep quality, and faster recovery. Individual results depend on baseline NAD+ levels, age, diet, and consistency of daily use.
Each serving is 2 capsules and delivers 750mg of pure Nicotinamide Mononucleotide (NMN) and 750mg of Trimethylglycine (TMG) — 1500mg of active ingredients total in a balanced 1:1 ratio. There are 30 servings per pouch (60 capsules), providing a 30-day supply.
NMN and TMG are both naturally occurring compounds found in foods and are generally well tolerated. As with any food supplement, some individuals may experience mild digestive discomfort, particularly when first starting. If you experience adverse reactions, discontinue use and consult a healthcare professional. If you are pregnant, breastfeeding, or taking medication, consult a doctor before use. Do not exceed the recommended daily dose.
Yes. Every batch is tested at an ISO/IEC 17025-accredited independent laboratory before release. The Certificate of Analysis (CoA) confirms identity and purity of both NMN and TMG, and the absence of heavy metals, pesticides, and microbiological contaminants. Email us with your batch number and we'll send it the same day.
Yes. The capsule shell is vegetable cellulose. The product is free from gluten, dairy, soy, nuts, and GMOs. 100% vegan and non-GMO verified. Manufactured in the United Kingdom.
Many customers include NMN + TMG as part of a broader daily protocol alongside other longevity supplements. As with any combination of supplements, we recommend consulting a healthcare professional if you are on medication or have an existing health condition.
We offer a 60-day money-back guarantee on all orders. If you are not completely satisfied for any reason, contact our customer support team within 60 days of purchase for a full refund. No questions asked.

60-Day Money-Back Guarantee

Try NMN + TMG for 60 days. If you're not completely satisfied for any reason, we'll refund you in full — no questions asked.

Longevity Series · NAD+ Complex

Start your
NAD+ protocol
today.

750mg NMN + 750mg TMG. Balanced 1:1 ratio. Third-party tested every batch. UK manufactured. 60-day guarantee.

Free UK delivery · 60-day guarantee · Cancel subscription anytime
Food Supplement Notice: Food supplements must not replace a varied, balanced diet and healthy lifestyle. If pregnant, breastfeeding or on medication, consult a doctor or qualified healthcare professional before use. Keep out of reach of children. Store below 25°C in a cool, dry place. Keep out of direct sunlight. Do not use if seal is broken. Do not exceed the recommended daily dose.

Claims Notice: This product is a food supplement. The statements on this page have not been evaluated by the MHRA. This product is not intended to diagnose, treat, cure, or prevent any disease. Health claims are made in accordance with applicable food supplement regulations.

Manufactured for: Vitality Supplements · 12 Deer Park Road, London SW19 3TL · vitality-supplements.co.uk
NMN
NMN + TMG 1500mg
60 Capsules · 30 Servings · Balanced 1:1 Ratio
£27.99