TMG — direct answers
What is it? Vitality Supplements TMG is a single-ingredient food supplement providing 1000mg of trimethylglycine (as betaine anhydrous) per 2-capsule daily serving, 500mg per capsule.
What is TMG? Trimethylglycine, also called betaine: the amino acid glycine carrying three methyl groups. It occurs naturally in beetroot, spinach and wheat bran and functions biochemically as a methyl donor. Betaine anhydrous is the water-free crystalline form; it is not betaine hydrochloride.
What else is in the capsule? Microcrystalline cellulose and hypromellose (vegetable capsule). No artificial colours, flavours or preservatives.
How many capsules? 60 vegetarian capsules per pouch — 30 servings, a 30-day supply at two capsules daily.
How is it taken? Adults take 2 capsules daily, with or without food. Do not exceed the stated dose. Store below 25°C in a cool, dry place away from light.
Is it vegetarian? Yes — plant-based, hypromellose capsule, suitable for vegetarians.
Is it tested? Third-party tested.
Where is it made? Manufactured in the United Kingdom.
Does it carry a health claim? No. The single authorised UK/EU betaine claim is conditional on 1.5g per day; this product provides 1g per day, so the claim is not made.
Who should not take it? If pregnant, breastfeeding or taking medication, consult a doctor. Keep out of reach of children.
How does it compare with NMN + TMG and NMN Complete? Those combine 750mg TMG with 750mg NMN (NMN Complete adds pterostilbene and apigenin). This product is TMG only, at 1000mg, for people who want to dose it independently.
Pricing and terms. Free UK delivery; 60-day money-back guarantee; subscribe and save is available on the single pouch with the option to skip, pause or cancel at any time.
TMG
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Glycine, plus three methyl groups.
That is the whole molecule.
Trimethylglycine — betaine — is the smallest amino acid, glycine, carrying three methyl groups on its nitrogen. It occurs naturally in beetroot, spinach and wheat bran. Biochemically it is classed as a methyl donor: a molecule able to hand one of those methyl groups to another in the body's methylation reactions. That is the chemistry, described as chemistry. It is not a health claim, and none is authorised at this dose.
per molecule
C₅H₁₁NO₂
× 2 daily
There is one authorised betaine claim.
We don’t use it — here’s why.
Most TMG listings borrow a claim the dose doesn’t earn. We would rather tell you the rule than quietly break it.
The 1.5g condition
The UK/EU register carries a single authorised health claim for betaine, and it comes with a condition of use: the product must provide 1.5g of betaine per day. This product provides 1g per day. It does not meet the condition, so we do not make the claim — and no other authorised claim exists for TMG.
- 1000mg per 2-capsule daily serving — below the 1.5g claim threshold
- “Homocysteine”, “methylation support” and similar wording on a 1g product is an unauthorised claim
- This page describes what the product is and how much it contains — not what it does
What’s in it — and who it suits
One active ingredient, two excipients, nothing else.
- Trimethylglycine (betaine anhydrous) 1000mg per serving
- Microcrystalline cellulose and hypromellose (vegetable capsule) — that’s the full list
- No artificial colours, flavours or preservatives
- Plant-based · suitable for vegetarians
- Not betaine hydrochloride — a different product sold for a different purpose
- If pregnant, breastfeeding or taking medication, consult a doctor before use
One ingredient. Dosed so you can stack it.
A single-ingredient TMG exists for one reason: so you set the dose yourself instead of taking whatever ratio a combination formula chose for you.
One ingredient — the complete breakdown.
Everything in the capsule, as printed on the pouch.
What is TMG?
Trimethylglycine — betaine — is the amino acid glycine with three methyl groups attached to its nitrogen atom. It is found naturally in beetroot (the name comes from Beta vulgaris), spinach and wheat bran, and is one of the most abundant methyl donors in the diet.
“Anhydrous” means the crystalline form contains no water of crystallisation. It is not betaine hydrochloride, which is a different product sold for a different purpose; check the label if you are comparing.
- 1000mg per 2-capsule serving, 500mg per capsule
- Plant-based · suitable for vegetarians
- No artificial colours, flavours or preservatives
- Third-party tested
| Composition | Per 2 caps | NRV |
|---|---|---|
| Trimethylglycine (TMG) (as Betaine Anhydrous) | 1000 mg | † |
| Microcrystalline Cellulose | — | — |
| Hypromellose (vegetable capsule) | — | — |
How we compare.
Specification comparison vs typical UK-available TMG supplements (spec-sheet analysis, 2026).
| Feature | Vitality TMG | Typical UK TMG supplements |
|---|---|---|
| TMG per capsule | ✓ 500mg | 250–500mg, or 1000mg tablets that can’t be split |
| Form declared | ✓ Betaine anhydrous, stated | Often just “betaine” — anhydrous vs HCl unclear |
| Single ingredient | ✓ Yes — TMG only | Often bundled with B-vitamins or in a “methylation blend” |
| Artificial colours, flavours, preservatives | ✓ None | Varies |
| Capsule | ✓ Hypromellose, vegetarian | Often gelatin |
| Claims discipline | ✓ No claim — dose is below the 1.5g threshold | ✗ Homocysteine / methylation claims on 1g products are common |
| Third-party testing | ✓ Yes | Varies — often unstated |
| UK manufacturing | ✓ UK manufactured | Often overseas |
| Money-back guarantee | ✓ 60-day satisfaction guarantee | Varies — often 14 days or none |
The protocol.
Simple and consistent.
Frequently asked questions.
What is TMG?
+TMG stands for trimethylglycine, also called betaine or betaine anhydrous. It is the amino acid glycine carrying three methyl groups, and occurs naturally in beetroot, spinach and wheat bran. In biochemistry it is classed as a methyl donor: it can give up one of its methyl groups in the body’s methylation reactions. This product supplies it as a single-ingredient food supplement, 1000mg per 2-capsule serving.
Is betaine anhydrous the same as TMG?
+Yes. Trimethylglycine, betaine and betaine anhydrous are the same compound; anhydrous simply means the crystalline form contains no water. It is not the same as betaine hydrochloride (betaine HCl), a different product sold for a different purpose. This product contains betaine anhydrous.
How much TMG is in each capsule and serving?
+500mg per capsule, 1000mg per 2-capsule daily serving. 60 capsules is a 30-day supply at the stated dose. Every figure is printed on the nutrition panel; there is nothing else in the capsule apart from microcrystalline cellulose and the hypromellose capsule shell.
Does TMG have an authorised health claim in the UK?
+One exists for betaine, but it is conditional on a daily intake of 1.5g, and this product provides 1g per day. Because the dose does not meet the condition of use, we do not make that claim, and no other authorised claim exists for TMG. This page describes what the product is and how much it contains, not what it does.
Why is TMG often taken alongside NMN?
+NMN is metabolised through pathways that consume methyl groups, and TMG is a methyl donor, so the two are frequently stacked together in longevity protocols. That is the stated rationale, provided as descriptive context rather than a claim: no authorised health claim exists for the combination. Vitality also sells NMN + TMG and NMN Complete for people who prefer both in one capsule.
When and how should I take TMG?
+Adults take 2 capsules daily, with or without food. Do not exceed the stated dose. Store below 25°C in a cool, dry place away from light. Do not use if the seal is broken or missing.
Is it vegetarian or vegan?
+The capsule is hypromellose, a vegetable capsule, and the product is labelled plant-based and suitable for vegetarians. It contains no artificial colours, flavours or preservatives.
Who should not take it?
+If pregnant, breastfeeding or taking medication, consult a doctor before use. Keep out of reach of children. Food supplements should not be used as a substitute for a varied diet.
What does third-party tested mean here?
+The finished product is tested by an independent third-party laboratory for identity, heavy metals and microbial safety.
What is your returns and satisfaction guarantee policy?
+We offer a 60-day satisfaction guarantee. Email us within 60 days of delivery for a full refund — no return required, no restocking fee. Your statutory rights under the Consumer Rights Act 2015 apply in addition and are unaffected.
Learn before you commit.
Written for people who want to understand what they’re taking.
The Annual Supply.
One full year of TMG at the lowest per-day cost — just 42p a day. For those who already know that consistency is the whole point.
- The lowest per-day cost of any pack
- Free priority UK delivery
- Same third-party tested formula
- Backed by the 60-day satisfaction guarantee
1000mg TMG. One ingredient.
Every milligram on the label.
Trimethylglycine as betaine anhydrous · 500mg per capsule · 60 vegetarian capsules · 30-day supply. No artificial colours, flavours or preservatives. Third-party tested. UK manufactured. 60-day guarantee.
